The Trichomonas vaginalis hydrogenosome proteome is highly reduced relative to mitochondria yet complex compared to mitosomes.
Schneider RE, Brown MT, Shiflett AM, Dyall SD, Hayes RD, Xie Y, Loo JA, and Johnson PJ. “The Trichomonas vaginalis hydrogenosome proteome is highly reduced relative to mitochondria yet complex compared to mitosomes.” Int J Parisitology 2011; 41: 1421-1434.
Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins.
Sinha S, Attar A, Maiti P, Du Z, Tan M, Pang ES, Lopes DHJ, Tseng C-H, Jones MR, Talbiersky P, Tennstädt A, Lichti-Kaiser K, Liu T, Yang F, Bakshi R, Kuo P-Y, Lomakin A, Gale GD, Benedek GB, Staudinger JL, Ehrmann M, Loo JA, Xie C-W, Klärner F-G, Schrader T, Wang C, Frautschy SA, and Bitan G. “Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins.” J Am Chem Soc 2011; 133: 16958–16969. (Chemical & Engineering News report: http://pubs.acs.org/cen/news/89/i40/8940notw4.html)
Concomitant Inhibition of HSP90, its Mitochondrial Localized Homologue TRAP1 and HSP27 by Green Tea in Pancreatic Cancer HPAF-II Cells.
Zhang L, Pang E, Ogorzalek Loo RR, Rao J, Go V-L W, Loo JA, and Lu Q-Y. “Concomitant Inhibition of HSP90, its Mitochondrial Localized Homologue TRAP1 and HSP27 by Green Tea in Pancreatic Cancer HPAF-II Cells.” Proteomics 2011; 11: 4638-4647.
Direct Ionization of Large Proteins and Protein Complexes by Desorption Electrospray Ionization-Mass Spectrometry.
Ferguson CN, Benchaar SA, Miao Z, Loo JA, and Chen H. “Direct Ionization of Large Proteins and Protein Complexes by Desorption Electrospray Ionization-Mass Spectrometry.” Anal Chem 2011; 83: 6468–6473. (Chemical & Engineering News report: http://pubs.acs.org/cen/email/html/8932scic2.html)
Characterization of Morphine-Glucose-6-Phosphate Dehydrogenase Conjugates by Mass Spectrometry.
Chiu ML, Ytterberg AJ, Ogorzalek Loo RR, Loo JA, and Monbouquette HG. “Characterization of Morphine-Glucose-6-Phosphate Dehydrogenase Conjugates by Mass Spectrometry.” Bioconj Chem 2011; 22: 1595-1604.
Systems biology approach in Chlamydomonas reveals connections between copper nutrition and multiple metabolic steps.
Castruita M, Casero D, Karpowicz SJ, Kropat J, Vieler A, Hsieh SI, Yan W, Cokus S, Loo JA, Benning C, Pellegrini M, and Merchant SS. “Systems biology approach in Chlamydomonas reveals connections between copper nutrition and multiple metabolic steps.” Plant Cell 2011; 23: 1273-1292.
Top-Down Mass Spectrometry of Supercharged Native Protein-Ligand Complexes.
Yin S and Loo JA. “Top-Down Mass Spectrometry of Supercharged Native Protein-Ligand Complexes.” Int J Mass Spectrom 2011; 300: 118-122.