A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A.
Dzialo MC, Travaglini KJ, Shen S, Loo JA, and Clarke SG. “A new type of protein lysine methyltransferase trimethylates Lys-79 of elongation factor 1A.” Biochem Biophys Res Commun 2014; 455: 382–389.
Radical directed dissociation of peptides and proteins by IRMPD and SORI-CID with FTICR mass spectrometry.
Zhang X, Li H, Moore B, Wongkongkathep P, Ogorzalek Loo RR, Loo JA, and Julian RR. “Radical directed dissociation of peptides and proteins by IRMPD and SORI-CID with FTICR mass spectrometry.” Rapid Commun Mass Spectrom 2014; 28: 2729-2734. PMCID: PMC4237167
Translational Roles of Elongation Factor 2 Protein Lysine Methylation.
Dzialo MC, Travaglini KJ, Shen S, Roy K, Chanfreau GF, Loo JA, and Clarke SG. “Translational Roles of Elongation Factor 2 Protein Lysine Methylation.” J Biol Chem 2014; 289: 30511-30524.
Sub-cellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas.
Hong-Hermesdorf A, Miethke M, Gallaher SD, Kropat J, Dodani SC, Chan J, Barupala D, Domaille DW, Shirasaki DI, Loo JA, Weber PK, Pett-Ridge J, Stemmler TL, Chang CJ, and Merchant SS. “Sub-cellular metal imaging identifies dynamic sites of Cu accumulation in Chlamydomonas.” Nature Chem Biol 2014; 10: 1034–1042.
Bioengineered Vaults: Self-Assembling Protein Shell-Lipophilic Core Nanoparticles for Drug Delivery.
Buehler DC, Marsden MD, Shen S, Toso DB, Wu X, Loo JA, Zhou ZH, Kickhoefer VA, Wender PA, Zack JA, and Rome LH. “Bioengineered Vaults: Self-Assembling Protein Shell-Lipophilic Core Nanoparticles for Drug Delivery.” ACS Nano 2014; 8: 7723-7732 (cover article).
What Protein Charging (and Supercharging) Reveal about the Mechanism of Electrospray Ionization.
Ogorzalek Loo RR, Lakshmanan R, and Loo JA. “What Protein Charging (and Supercharging) Reveal about the Mechanism of Electrospray Ionization.” J Am Soc Mass Spectrom 2014; 25: 1675-1693.
Revealing Ligand Binding Sites and Quantifying Subunit Variants of Non-Covalent Protein Complexes in a Single Native Top-Down FTICR MS Experiment.
Li H, Wongkongkathep P, Van Orden SL, Ogorzalek Loo RR, and Loo JA. “Revealing Ligand Binding Sites and Quantifying Subunit Variants of Non-Covalent Protein Complexes in a Single Native Top-Down FTICR MS Experiment.” J Am Soc Mass Spectrom 2014; 25: 2060-2068.
Proteomics Detection of Endothelial Cell Surface Proteins Following Irradiation as Potential Targets for Brain Arteriovenous Malformations Molecular Therapy.
Simonian M, Ogorzalek Loo RR, Loo JA, Stoodley MA, and Molloy MP. “Proteomics Detection of Endothelial Cell Surface Proteins Following Irradiation as Potential Targets for Brain Arteriovenous Malformations Molecular Therapy.” MOJ Proteomics Bioinform 2014; 1: 00002 (6 pp.).
Decoy Plasminogen Receptor Containing a Selective Kunitz-Inhibitory Domain.
Kumar Y, Vadivel K, Schmidt AE, Ogueli GI, Ponnuraj SM, Rannulu N, Loo JA, Bajaj MS, and Bajaj SP. “Decoy Plasminogen Receptor Containing a Selective Kunitz-Inhibitory Domain.” Biochemistry 2014; 53, 505−517.
Native Top-Down Electrospray Ionization-Mass Spectrometry of 158 kDa Protein Complex by High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.
Li H, Wolff JJ, Van Orden SL, and Loo JA. “Native Top-Down Electrospray Ionization-Mass Spectrometry of 158 kDa Protein Complex by High-Resolution Fourier Transform Ion Cyclotron Resonance Mass Spectrometry.” Anal Chem 2014; 86: 317−320 (cover article).
Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer.
Acharya S, Safaie BM, Wongkongkathep P, Ivanova MI, Attar A, Klärner F-G, Schrader T, Loo JA, Bitan G, and Lapidus LJ. “Molecular Basis for Preventing α-Synuclein Aggregation by a Molecular Tweezer.” J Biol Chem 2014; 289: 10727-10737.
Enhanced FASP (eFASP) to Increase Proteome Coverage and Sample Recovery for Quantitative Proteomic Experiments.
Erde J, Ogorzalek Loo RR, and Loo JA. “Enhanced FASP (eFASP) to Increase Proteome Coverage and Sample Recovery for Quantitative Proteomic Experiments.” J Proteome Res 2014; 13: 1885−1895. (Comment in BioTechniques, May 2014; 56: 211) (Listed as one of the “Ten of the most interesting papers from Journal of Proteome Research in 2015; C&EN Supplement, December 2015).
Top-Down Protein Identification of Proteasome Proteins with nanoLC FT-ICR MS Employing Data-Independent Fragmentation Methods.
Lakshmanan R, Wolff J, Alvarado R, and Loo JA. “Top-Down Protein Identification of Proteasome Proteins with nanoLC FT-ICR MS Employing Data-Independent Fragmentation Methods.” Proteomics 2014; 14: 1271-1282.
Addressing the Needs of Traumatic Brain Injury with Clinical Proteomics.
Shen S, Ogorzalek Loo RR, Wanner I-B, and Loo JA. “Addressing the Needs of Traumatic Brain Injury with Clinical Proteomics.” Clin Proteomics 2014; 11: 11 (13 pp.).